Anti-MAP3K4 antibody [R05-8A5] (STJA0035260)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthetic peptide of human MAP3K4
General Information
| Short Description | Rabbit monoclonal anti-MAP3K4 for use in WB, IHC-F, IHC-P, ICC and IF in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-F/IHC-P/ICC/IF |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | R05-8A5 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.3 mg/mL |
| Purification | Affinity Purified |
| Dilution Range | WB 1:500-1:1000IHC 1:50-1:100IF 1:50-1:200 |
| Formulation | 50mM Tris-Glycine (pH 7.4) , 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | MAP3K4 |
| Gene ID | 4216 |
| Uniprot ID | M3K4_HUMAN |
| Immunogen | A synthetic peptide of human MAP3K4 |
Additional Info
| Tissue Specificity | Expressed at high levels in heart, placenta, skeletal muscle and pancreas, and at lower levels in other tissues. |
| Function | Component of a protein kinase signal transduction cascade. Activates the CSBP2, P38 and JNK MAPK pathways, but not the ERK pathway. Specifically phosphorylates and activates MAP2K4 and MAP2K6. |
| Protein Name | Mitogen-Activated Protein Kinase Kinase Kinase 4Map Three Kinase 1Mapk/Erk Kinase Kinase 4Mek Kinase 4Mekk 4 |
| Database Links | |
| Cellular Localisation | CytoplasmPerinuclear RegionLocalized In Perinuclear Vesicular-Like StructuresProbably Golgi-Associated Vesicles |
| Alternative Antibody Names | Anti-Mitogen-Activated Protein Kinase Kinase Kinase 4 antibodyAnti-Map Three Kinase 1 antibodyAnti-Mapk/Erk Kinase Kinase 4 antibodyAnti-Mek Kinase 4 antibodyAnti-Mekk 4 antibodyAnti-MAP3K4 antibodyAnti-KIAA0213 antibodyAnti-MAPKKK4 antibodyAnti-MEKK4 antibodyAnti-MTK1 antibody |
Information sourced from Uniprot.org