Anti-MAP3K21 antibody (631-680) (STJ94152)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from human MAP3KL4. AA range:631-680
General Information
| Short Description | Rabbit polyclonal anti-Mitogen-activated protein kinase kinase kinase 21 (631-680) for use in WB, ELISA and IHC in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA/IHC |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000IHC-p 1:50-300ELISA 2000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | MAP3K21 |
| Gene ID | 84451 |
| Uniprot ID | M3K21_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from human MAP3KL4. AA range:631-680 |
| Immunogen Region | 631-680 |
| Specificity | MLK4 Polyclonal Antibody detects endogenous levels of MLK4 protein. |
Additional Info
| Post Translational Modifications | Autophosphorylation on serine and threonine residues within the activation loop plays a role in enzyme activation. |
| Function | Negative regulator of TLR4 signaling. Does not activate JNK1/MAPK8 pathway, p38/MAPK14, nor ERK2/MAPK1 pathways. |
| Protein Name | Mitogen-Activated Protein Kinase Kinase Kinase 21Mitogen-Activated Protein Kinase Kinase Kinase Mlk4Mixed Lineage Kinase 4 |
| Database Links | |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Mitogen-Activated Protein Kinase Kinase Kinase 21 antibodyAnti-Mitogen-Activated Protein Kinase Kinase Kinase Mlk4 antibodyAnti-Mixed Lineage Kinase 4 antibodyAnti-MAP3K21 antibodyAnti-KIAA1804 antibodyAnti-MLK4 antibody |
Information sourced from Uniprot.org