Anti-MAP3K2 antibody (11-27 aa) [R06-2K7] (STJA0011589)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthetic peptide of human MEKK2
General Information
| Short Description | Rabbit monoclonal anti-MEKK2 (11-27 aa) for use in WB, ICC, IF and IP in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ICC/IF/IP |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | R06-2K7 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.3 mg/mL |
| Purification | Affinity Purified |
| Dilution Range | WB 1:500-1:1000IF 1:50-1:200IP 1:20 |
| Formulation | 50mM Tris-Glycine (pH7.4) , 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | MAP3K2 |
| Gene ID | 10746 |
| Uniprot ID | M3K2_HUMAN |
| Immunogen | A synthetic peptide of human MEKK2 |
| Immunogen Region | 11-27 aa |
Additional Info
| Post Translational Modifications | Autophosphorylated. Ubiquitination by XIAP/BIRC4 does not lead to proteasomal degradation. |
| Function | Component of a protein kinase signal transduction cascade. Regulates the JNK and ERK5 pathways by phosphorylating and activating MAP2K5 and MAP2K7. Plays a role in caveolae kiss-and-run dynamics. |
| Protein Name | Mitogen-Activated Protein Kinase Kinase Kinase 2Mapk/Erk Kinase Kinase 2Mek Kinase 2Mekk 2 |
| Database Links | |
| Cellular Localisation | CytoplasmNucleusUpon Egf StimulationTranslocates Into The Nucleus |
| Alternative Antibody Names | Anti-Mitogen-Activated Protein Kinase Kinase Kinase 2 antibodyAnti-Mapk/Erk Kinase Kinase 2 antibodyAnti-Mek Kinase 2 antibodyAnti-Mekk 2 antibodyAnti-MAP3K2 antibodyAnti-MAPKKK2 antibodyAnti-MEKK2 antibody |
Information sourced from Uniprot.org