Host: |
Rabbit |
Applications: |
WB/IHC/IF/ELISA |
Reactivity: |
Human/Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-Mitogen-activated protein kinase kinase kinase 13 (151-200 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: |
1 mg/mL |
Dilution Range: |
WB 1:500-1:2000IHC 1:100-1:300ELISA 1:20000IF 1:50-200 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
MAP3K13 |
Gene ID: |
9175 |
Uniprot ID: |
M3K13_HUMAN |
Immunogen Region: |
151-200 aa |
Specificity: |
LZK Polyclonal Antibody detects endogenous levels of LZK protein. |
Immunogen: |
The antiserum was produced against synthesized peptide derived from the human M3K13 at the amino acid range 151-200 |
Post Translational Modifications | Autophosphorylated on serine and threonine residues. |
Function | Activates the JUN N-terminal pathway through activation of the MAP kinase kinase MAP2K7. Acts synergistically with PRDX3 to regulate the activation of NF-kappa-B in the cytosol. This activation is kinase-dependent and involves activating the IKK complex, the IKBKB-containing complex that phosphorylates inhibitors of NF-kappa-B. |
Protein Name | Mitogen-Activated Protein Kinase Kinase Kinase 13Leucine Zipper-Bearing KinaseMixed Lineage KinaseMlk |
Cellular Localisation | CytoplasmMembranePeripheral Membrane Protein |
Alternative Antibody Names | Anti-Mitogen-Activated Protein Kinase Kinase Kinase 13 antibodyAnti-Leucine Zipper-Bearing Kinase antibodyAnti-Mixed Lineage Kinase antibodyAnti-Mlk antibodyAnti-MAP3K13 antibodyAnti-LZK antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance