| Host: |
Mouse |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Mouse monoclonal antibody anti-Dual specificity mitogen-activated protein kinase kinase 5 is suitable for use in Western Blot research applications. |
| Clonality: |
Monoclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
MAP2K5 |
| Gene ID: |
5607 |
| Uniprot ID: |
MP2K5_HUMAN |
| Specificity: |
This antibody detects endogenous levels of MEK5 at Human, Mouse, Rat |
| Immunogen: |
Synthesized peptide derived from the human MEK5 |
| Post Translational Modifications | Activated by phosphorylation on Ser/Thr by MAP kinase kinase kinases. (Microbial infection) Yersinia YopJ may acetylate Ser/Thr residues, preventing phosphorylation and activation, thus blocking the MAPK signaling pathway. |
| Function | Acts as a scaffold for the formation of a ternary MAP3K2/MAP3K3-MAP3K5-MAPK7 signaling complex. Activation of this pathway appears to play a critical role in protecting cells from stress-induced apoptosis, neuronal survival and cardiac development and angiogenesis. |
| Protein Name | Dual Specificity Mitogen-Activated Protein Kinase Kinase 5Map Kinase Kinase 5Mapkk 5Mapk/Erk Kinase 5Mek 5 |
| Database Links | Reactome: R-HSA-198765 |
| Alternative Antibody Names | Anti-Dual Specificity Mitogen-Activated Protein Kinase Kinase 5 antibodyAnti-Map Kinase Kinase 5 antibodyAnti-Mapkk 5 antibodyAnti-Mapk/Erk Kinase 5 antibodyAnti-Mek 5 antibodyAnti-MAP2K5 antibodyAnti-MEK5 antibodyAnti-MKK5 antibodyAnti-PRKMK5 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
