Anti-MAOA antibody (428-527) [S7MR] (STJ11101997)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal Monoamine Oxidase A (428-527) antibody for use in WB, IHC-P and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | S7MR |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:1000-1:6000IHC-P:1:1000-1:4000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | MAOA |
| Gene ID | 4128 |
| Uniprot ID | AOFA_HUMAN |
| Immunogen Region | 428-527 |
| Immunogen Sequence | GRIFFAGTETATKWSGYMEG AVEAGERAAREVLNGLGKVT EKDIWVQEPESKDVPAVEIT HTFWERNLPSVSGLLKIIGF STSVTALGFVLYKYKLLPRS |
| Specificity | A synthetic peptide corresponding to a sequence within amino acids 428-527 of human Monoamine Oxidase A (MAOA) (P21397). |
Additional Info
| Tissue Specificity | Heart, liver, duodenum, blood vessels and kidney. |
| Function | Catalyzes the oxidative deamination of primary and some secondary amine such as neurotransmitters, with concomitant reduction of oxygen to hydrogen peroxide and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. Preferentially oxidizes serotonin. Also catalyzes the oxidative deamination of kynuramine to 3-(2-aminophenyl)-3-oxopropanal that can spontaneously condense to 4-hydroxyquinoline. |
| Protein Name | Amine Oxidase Flavin-Containing AMonoamine Oxidase Type AMao-A |
| Database Links | Reactome: R-HSA-141333Reactome: R-HSA-181430Reactome: R-HSA-379397Reactome: R-HSA-379398Reactome: R-HSA-379401Reactome: R-HSA-380612Reactome: R-HSA-5579012Reactome: R-HSA-6785807 |
| Cellular Localisation | Mitochondrion Outer MembraneSingle-Pass Type Iv Membrane ProteinCytoplasmic Side |
| Alternative Antibody Names | Anti-Amine Oxidase Flavin-Containing A antibodyAnti-Monoamine Oxidase Type A antibodyAnti-Mao-A antibodyAnti-MAOA antibody |
Information sourced from Uniprot.org