| Short Description : | Rabbit polyclonal MAGEA11 (1-110) antibody for use in WB and ELISA in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/ELISA |
| Host: | Rabbit |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:200-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | MAGEA11 |
| Gene ID: | 4110 |
| Uniprot ID: | MAGAB_HUMAN |
| Immunogen Region: | 1-110 |
| Immunogen Sequence: | METQFRRGGLGCSPASIKRK KKREDSGDFGLQVSTMFSED DFQSTERAPYGPQLQWSQDL PRVQVFREQANLEDRSPRRT QRITGGEQVLWGPITQIFPT VRPADLTRVI |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-110 of human MAGEA11 (NP_005357.2). |
| Tissue Specificity | Expressed in tumors of several types, such as melanoma, head and neck squamous cell carcinoma, lung carcinoma and breast carcinoma. Expressed in testis, ovary, prostate, cancerous prostate, breast and adrenal tissue. |
| Function | Acts as androgen receptor coregulator that increases androgen receptor activity by modulating the receptors interdomain interaction. May play a role in embryonal development and tumor transformation or aspects of tumor progression. |
| Protein Name | Melanoma-Associated Antigen 11Cancer/Testis Antigen 1.11Ct1.11Mage-11 Antigen |
| Database Links | |
| Cellular Localisation | NucleusCytoplasm |
| Alternative Antibody Names | Anti-Melanoma-Associated Antigen 11 antibodyAnti-Cancer/Testis Antigen 1.11 antibodyAnti-Ct1.11 antibodyAnti-Mage-11 Antigen antibodyAnti-MAGEA11 antibodyAnti-MAGE11 antibody |
Information sourced from Uniprot.org
