| Host: | Rabbit |
| Applications: | IHC/IF/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Transcription factor MafF (51-100 aa) is suitable for use in Immunohistochemistry, Immunofluorescence and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | IHC 1:100-1:300ELISA 1:10000IF 1:50-200 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | MAFF |
| Gene ID: | 23764 |
| Uniprot ID: | MAFF_HUMAN |
| Immunogen Region: | 51-100 aa |
| Specificity: | MafF Polyclonal Antibody detects endogenous levels of MafF protein. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human MAFF at the amino acid range 51-100 |
| Function | Since they lack a putative transactivation domain, the small Mafs behave as transcriptional repressors when they dimerize among themselves. However, they seem to serve as transcriptional activators by dimerizing with other (usually larger) basic-zipper proteins, such as NFE2L1/NRF1, and recruiting them to specific DNA-binding sites. Interacts with the upstream promoter region of the oxytocin receptor gene. May be a transcriptional enhancer in the up-regulation of the oxytocin receptor gene at parturition. |
| Protein Name | Transcription Factor MaffU-MafV-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog F |
| Database Links | Reactome: R-HSA-983231 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Transcription Factor Maff antibodyAnti-U-Maf antibodyAnti-V-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog F antibodyAnti-MAFF antibody |
Information sourced from Uniprot.org