| Host: |
Mouse |
| Applications: |
ELISA/FC/IHC-P/WB |
| Reactivity: |
Human/Camel |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Mouse monoclonal antibody anti-MAdCAM-1 is suitable for use in ELISA, Flow Cytometry, Immunohistochemistry and Western Blot research applications. |
| Clonality: |
Monoclonal |
| Clone ID: |
17F5 |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG1 |
| Formulation: |
PBS with <0.1% sodium azide |
| Purification: |
Purified |
| Concentration: |
1 mg/mL |
| Storage Instruction: |
Store aliquots at-20°C, and thawed aliquots at 2-8°C. |
| Immunogen: |
Recombinant soluble MAdCAM-1-fc fusion protein |
| Background | Mouse anti Human MAdCAM-1 antibody, clone 17F5 recognizes human mucosal addressin cell adhesion molecule 1 (MAdCAM-1) a ~60 kDa transmembrane protein that belongs to the immunoglobulin superfamily. MAdCAM-1 is strongly expressed on mucosal lymphoid tissue and high endothelial venules of Peyer s patches. Human MAdCAM-1 interacts with the beta 7 integrin LPAM-1 (alpha4beta7) , CD62L, and VLA-4 (alpha4beta1) and is involved in lymphocyte trafficking, Mouse anti Human MAdCAM-1 antibody, clone 17F5 recognizes the mucin domain of MAdCAM-1. This antibody does not block the function of MAdCAM-1 (Leung, E. et al. 2004). |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
