Anti-MAD2L1BP antibody (175-274) [S0MR] (STJ11103050)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal MAD2L1BP (175-274) antibody for use in WB, IHC-P and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | S0MR |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | MAD2L1BP |
| Gene ID | 9587 |
| Uniprot ID | MD2BP_HUMAN |
| Immunogen Region | 175-274 |
| Immunogen Sequence | YSVDQSLSTAACLRRLFRAI FMADAFSELQAPPLMGTVVM AQGHRNCGEDWFRPKLNYRV PSRGHKLTVTLSCGRPSIRT TAWEDYIWFQAPVTFKGFRE |
| Specificity | A synthetic peptide corresponding to a sequence within amino acids 175-274 of human MAD2L1BP (Q15013). |
Additional Info
| Function | May function to silence the spindle checkpoint and allow mitosis to proceed through anaphase by binding MAD2L1 after it has become dissociated from the MAD2L1-CDC20 complex. |
| Protein Name | Mad2l1-Binding ProteinCaught By Mad2 ProteinP31(Comet |
| Database Links | |
| Cellular Localisation | NucleusCytoplasmCytoskeletonSpindleDuring Early MitosisUnevenly Distributed Throughout The NucleoplasmFrom Metaphase To AnaphaseConcentrated On The Spindle |
| Alternative Antibody Names | Anti-Mad2l1-Binding Protein antibodyAnti-Caught By Mad2 Protein antibodyAnti-P31(Comet antibodyAnti-MAD2L1BP antibodyAnti-CMT2 antibodyAnti-KIAA0110 antibody |
Information sourced from Uniprot.org