Anti-M6PR antibody [R09-8E3] (STJA0037307)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthesized peptide derived from human M6PR
General Information
| Short Description | Rabbit monoclonal anti-M6PR for use in WB, ICC, IF and FC in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ICC/IF/FC |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | R09-8E3 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Affinity Purified |
| Dilution Range | WB 1:500-1:1000IF 1:50-1:200FC 1:50-1:100 |
| Formulation | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | M6PR |
| Gene ID | 4074 |
| Uniprot ID | MPRD_HUMAN |
| Immunogen | A synthesized peptide derived from human M6PR |
Additional Info
| Function | Transport of phosphorylated lysosomal enzymes from the Golgi complex and the cell surface to lysosomes. Lysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose-6-phosphate receptors in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelyosomal compartment where the low pH mediates the dissociation of the complex. |
| Protein Name | Cation-Dependent Mannose-6-Phosphate ReceptorCd Man-6-P ReceptorCd-Mpr46 Kda Mannose 6-Phosphate ReceptorMpr 46 |
| Database Links | Reactome: R-HSA-432720Reactome: R-HSA-6811440Reactome: R-HSA-8856825Reactome: R-HSA-8856828Reactome: R-HSA-9840310 |
| Cellular Localisation | Lysosome MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Cation-Dependent Mannose-6-Phosphate Receptor antibodyAnti-Cd Man-6-P Receptor antibodyAnti-Cd-Mpr antibodyAnti-46 Kda Mannose 6-Phosphate Receptor antibodyAnti-Mpr 46 antibodyAnti-M6PR antibodyAnti-MPR46 antibodyAnti-MPRD antibody |
Information sourced from Uniprot.org