Anti-LZTS1 antibody (STJA0007961)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human LZTS1
General Information
| Short Description | Rabbit polyclonal anti-Leucine zipper putative tumor suppressor 1 for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | LZTS1 |
| Gene ID | 11178 |
| Uniprot ID | LZTS1_HUMAN |
| Immunogen | Synthesized peptide derived from human LZTS1 |
| Specificity | This antibody detects endogenous levels of LZTS1 at Human, Mouse, Rat |
Additional Info
| Post Translational Modifications | Phosphorylated on serine residues. Hyperphosphorylated by the cAMP-dependent kinase PKA during cell-cycle progression. |
| Function | Involved in the regulation of cell growth. May stabilize the active CDC2-cyclin B1 complex and thereby contribute to the regulation of the cell cycle and the prevention of uncontrolled cell proliferation. May act as a tumor suppressor. |
| Protein Name | Leucine Zipper Putative Tumor Suppressor 1F37/Esophageal Cancer-Related Gene-Coding Leucine-Zipper MotifFez1 |
| Database Links | |
| Cellular Localisation | CytoplasmCell MembraneCell ProjectionDendritic SpinePostsynaptic DensitySynapseAssociated With The Plasma Membrane And With MicrotubulesDetected In Dendritic SpinesEspecially In The Postsynaptic Density |
| Alternative Antibody Names | Anti-Leucine Zipper Putative Tumor Suppressor 1 antibodyAnti-F37/Esophageal Cancer-Related Gene-Coding Leucine-Zipper Motif antibodyAnti-Fez1 antibodyAnti-LZTS1 antibodyAnti-FEZ1 antibody |
Information sourced from Uniprot.org