Anti-LZTR1 antibody (310-390 aa) (STJ191772)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human protein at the amino acid range 310-390
General Information
| Short Description | Rabbit polyclonal anti-Leucine-zipper-like transcriptional regulator 1 (310-390 aa) for use in WB and ELISA in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | LZTR1 |
| Gene ID | 8216 |
| Uniprot ID | LZTR1_HUMAN |
| Immunogen | Synthesized peptide derived from the human protein at the amino acid range 310-390 |
| Immunogen Region | 310-390 aa |
| Specificity | LZTR1 Polyclonal Antibody detects endogenous levels of protein. |
Additional Info
| Function | Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex that mediates ubiquitination of Ras (K-Ras/KRAS, N-Ras/NRAS and H-Ras/HRAS). Is a negative regulator of RAS-MAPK signaling that acts by controlling Ras levels and decreasing Ras association with membranes. |
| Protein Name | Leucine-Zipper-Like Transcriptional Regulator 1Lztr-1 |
| Database Links | |
| Cellular Localisation | Endomembrane SystemRecycling EndosomeGolgi Apparatus |
| Alternative Antibody Names | Anti-Leucine-Zipper-Like Transcriptional Regulator 1 antibodyAnti-Lztr-1 antibodyAnti-LZTR1 antibodyAnti-TCFL2 antibody |
Information sourced from Uniprot.org