Anti-Lymphotoxin alpha antibody [R08-7H6] (STJA0036452)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthesized peptide derived from human TNF beta
General Information
| Short Description | Rabbit monoclonal anti-Lymphotoxin alpha for use in WB in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | R08-7H6 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Affinity Chromatography |
| Dilution Range | WB 1:500-1:1000 |
| Formulation | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | LTA |
| Gene ID | 4049 |
| Uniprot ID | TNFB_HUMAN |
| Immunogen | A synthesized peptide derived from human TNF beta |
Additional Info
| Function | Cytokine that in its homotrimeric form binds to TNFRSF1A/TNFR1, TNFRSF1B/TNFBR and TNFRSF14/HVEM. In its heterotrimeric form with LTB binds to TNFRSF3/LTBR. Lymphotoxin is produced by lymphocytes and is cytotoxic for a wide range of tumor cells in vitro and in vivo. |
| Protein Name | Lymphotoxin-AlphaLt-AlphaTnf-BetaTumor Necrosis Factor Ligand Superfamily Member 1 |
| Database Links | Reactome: R-HSA-5668541Reactome: R-HSA-5669034Reactome: R-HSA-5676594 |
| Cellular Localisation | SecretedMembraneThe Homotrimer Is SecretedThe Heterotrimer Is Membrane-Associated |
| Alternative Antibody Names | Anti-Lymphotoxin-Alpha antibodyAnti-Lt-Alpha antibodyAnti-Tnf-Beta antibodyAnti-Tumor Necrosis Factor Ligand Superfamily Member 1 antibodyAnti-LTA antibodyAnti-TNFB antibodyAnti-TNFSF1 antibody |
Information sourced from Uniprot.org