Anti-LY75 antibody (STJA0037858)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthesized peptide derived from human CD205
General Information
| Short Description | Rabbit monoclonal anti-LY75 for use in IHC-P in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC-P |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Affinity Purified |
| Dilution Range | IHC 1:100-1:200 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3. |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | LY75 |
| Gene ID | 100526664/4065 |
| Uniprot ID | LY75_HUMAN |
| Immunogen | A synthesized peptide derived from human CD205 |
Additional Info
| Tissue Specificity | Expressed in spleen, thymus, colon and peripheral blood lymphocytes. Detected in myeloid and B-lymphoid cell lines. Isoform 2 and isoform 3 are expressed in malignant Hodgkin lymphoma cells called Hodgkin and Reed-Sternberg (HRS) cells. |
| Post Translational Modifications | N-glycosylated. |
| Function | Acts as an endocytic receptor to direct captured antigens from the extracellular space to a specialized antigen-processing compartment. Causes reduced proliferation of B-lymphocytes. |
| Protein Name | Lymphocyte Antigen 75Ly-75C-Type Lectin Domain Family 13 Member BDec-205Gp200-Mr6Cd Antigen Cd205 |
| Database Links | |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Lymphocyte Antigen 75 antibodyAnti-Ly-75 antibodyAnti-C-Type Lectin Domain Family 13 Member B antibodyAnti-Dec-205 antibodyAnti-Gp200-Mr6 antibodyAnti-Cd Antigen Cd205 antibodyAnti-LY75 antibodyAnti-CD205 antibodyAnti-CLEC13B antibody |
Information sourced from Uniprot.org