| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-E3 ubiquitin-protein ligase listerin is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
LTN1 |
| Gene ID: |
26046 |
| Uniprot ID: |
LTN1_HUMAN |
| Specificity: |
This antibody detects endogenous levels of RNF160 at Human, Mouse |
| Immunogen: |
Synthesized peptide derived from human RNF160 |
| Function | E3 ubiquitin-protein ligase component of the ribosome quality control complex (RQC), a ribosome-associated complex that mediates ubiquitination and extraction of incompletely synthesized nascent chains for proteasomal degradation. Within the RQC complex, LTN1 is recruited to stalled 60S ribosomal subunits by NEMF and mediates ubiquitination of stalled nascent chains. Ubiquitination leads to VCP/p97 recruitment for extraction and degradation of the incomplete translation product. |
| Protein Name | E3 Ubiquitin-Protein Ligase ListerinRing Finger Protein 160Ring-Type E3 Ubiquitin Transferase ListerinZinc Finger Protein 294 |
| Database Links | Reactome: R-HSA-983168 |
| Cellular Localisation | CytoplasmCytosol |
| Alternative Antibody Names | Anti-E3 Ubiquitin-Protein Ligase Listerin antibodyAnti-Ring Finger Protein 160 antibodyAnti-Ring-Type E3 Ubiquitin Transferase Listerin antibodyAnti-Zinc Finger Protein 294 antibodyAnti-LTN1 antibodyAnti-C21orf10 antibodyAnti-C21orf98 antibodyAnti-KIAA0714 antibodyAnti-RNF160 antibodyAnti-ZNF294 antibodyAnti-HSPC087 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
