• Western blot analysis of the lysates from HeLa cells using LTK antibody.
  • Western blot analysis of lysates from Jurkat cells, using LTK Antibody. The lane on the right is blocked with the synthesized peptide.

Anti-LTK antibody (206-255 aa) (STJ93963)

SKU:
STJ93963

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Leukocyte tyrosine kinase receptor (206-255 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC 1:100-1:300
IF 1:200-1:1000
ELISA 1:5000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: LTK
Gene ID: 4058
Uniprot ID: LTK_HUMAN
Immunogen Region: 206-255 aa
Specificity: LTK Polyclonal Antibody detects endogenous levels of LTK protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human LTK at the amino acid range 206-255
Post Translational Modifications Phosphorylated at tyrosine residues by autocatalysis, which activates kinase activity.
Function Receptor with a tyrosine-protein kinase activity. Following activation by ALKAL1 or ALKAL2 ligands at the cell surface, transduces an extracellular signal into an intracellular response. Ligand-binding to the extracellular domain induces tyrosine kinase activation, leading to activation of the mitogen-activated protein kinase (MAPK) pathway. Phosphorylates almost exclusively at the first tyrosine of the Y-x-x-x-Y-Y motif. The exact function of this protein is not known.studies with chimeric proteins demonstrate its ability to promote growth and specifically neurite outgrowth, and cell survival. Involved in regulation of the secretory pathway involving endoplasmic reticulum (ER) export sites (ERESs) and ER to Golgi transport.
Protein Name Leukocyte Tyrosine Kinase Receptor
Protein Tyrosine Kinase 1
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Alternative Antibody Names Anti-Leukocyte Tyrosine Kinase Receptor antibody
Anti-Protein Tyrosine Kinase 1 antibody
Anti-LTK antibody
Anti-TYK1 antibody

Information sourced from Uniprot.org

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