Anti-LTBR antibody (336-435) (STJ27304)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal LTBR (336-435) antibody for use in WB, IHC-P, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000IHC-P:1:50-1:200IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | LTBR |
| Gene ID | 4055 |
| Uniprot ID | TNR3_HUMAN |
| Immunogen Region | 336-435 |
| Immunogen Sequence | GEQSQVAHGTNGIHVTGGSM TITGNIYIYNGPVLGGPPGP GDLPATPEPPYPIPEEGDPG PPGLSTPHQEDGKAWHLAET EHCGATPSNRGPRNQFITHD |
| Specificity | A synthetic peptide corresponding to a sequence within amino acids 336-435 of human LTBR (NP_002333.1). |
Additional Info
| Function | Receptor for the heterotrimeric lymphotoxin containing LTA and LTB, and for TNFS14/LIGHT. Activates NF-kappa-B signaling pathway upon stimulation with lymphotoxin (LTA(1)-LTB(2)). Promotes apoptosis via TRAF3 and TRAF5. May play a role in the development of lymphoid organs. |
| Protein Name | Tumor Necrosis Factor Receptor Superfamily Member 3Lymphotoxin-Beta ReceptorTumor Necrosis Factor C ReceptorTumor Necrosis Factor Receptor 2-Related ProteinTumor Necrosis Factor Receptor Type IiiTnf-RiiiTnfr-Iii |
| Database Links | Reactome: R-HSA-5668541Reactome: R-HSA-5676594 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Tumor Necrosis Factor Receptor Superfamily Member 3 antibodyAnti-Lymphotoxin-Beta Receptor antibodyAnti-Tumor Necrosis Factor C Receptor antibodyAnti-Tumor Necrosis Factor Receptor 2-Related Protein antibodyAnti-Tumor Necrosis Factor Receptor Type Iii antibodyAnti-Tnf-Riii antibodyAnti-Tnfr-Iii antibodyAnti-LTBR antibodyAnti-D12S370 antibodyAnti-TNFCR antibodyAnti-TNFR3 antibodyAnti-TNFRSF3 antibody |
Information sourced from Uniprot.org