Anti-LTB4R antibody (STJ192664)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from part of the human protein
General Information
| Short Description | Rabbit polyclonal anti-Leukotriene B4 receptor 1 for use in WB and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | LTB4R |
| Gene ID | 1241 |
| Uniprot ID | LT4R1_HUMAN |
| Immunogen | Synthesized peptide derived from part of the human protein |
| Specificity | LT4R1 Polyclonal Antibody detects endogenous levels of protein. |
Additional Info
| Post Translational Modifications | Phosphorylated by GRK6 upon leukotriene B4 binding.which promotes desensitization. |
| Function | Receptor for extracellular ATP > UTP and ADP. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. May be the cardiac P2Y receptor involved in the regulation of cardiac muscle contraction through modulation of L-type calcium currents. Is a receptor for leukotriene B4, a potent chemoattractant involved in inflammation and immune response. |
| Protein Name | Leukotriene B4 Receptor 1Ltb4-R 1Ltb4-R1Chemoattractant Receptor-Like 1G-Protein Coupled Receptor 16P2y Purinoceptor 7P2y7 |
| Database Links | Reactome: R-HSA-391906Reactome: R-HSA-416476 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Leukotriene B4 Receptor 1 antibodyAnti-Ltb4-R 1 antibodyAnti-Ltb4-R1 antibodyAnti-Chemoattractant Receptor-Like 1 antibodyAnti-G-Protein Coupled Receptor 16 antibodyAnti-P2y Purinoceptor 7 antibodyAnti-P2y7 antibodyAnti-LTB4R antibodyAnti-BLT antibodyAnti-BLT1 antibodyAnti-BLTR antibodyAnti-CMKRL1 antibodyAnti-GPR16 antibodyAnti-P2RY7 antibody |
Information sourced from Uniprot.org