| Short Description : | Rabbit polyclonal anti-Lanosterol synthase for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 1 mg/mL |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range: | WB 1:500-2000 |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | LSS |
| Gene ID: | 4047 |
| Uniprot ID: | LSS_HUMAN |
| Immunogen: | Synthesized peptide derived from human LSS |
| Specificity: | This antibody detects endogenous levels of LSS at Human, Mouse, Rat |
| Function | Key enzyme in the cholesterol biosynthesis pathway. Catalyzes the cyclization of (S)-2,3 oxidosqualene to lanosterol, a reaction that forms the sterol nucleus. Through the production of lanosterol may regulate lens protein aggregation and increase transparency. |
| Protein Name | Lanosterol Synthase2 -3-Epoxysqualene--Lanosterol CyclaseOxidosqualene--Lanosterol CyclaseOscHosc |
| Database Links | Reactome: R-HSA-191273Reactome: R-HSA-2426168 |
| Cellular Localisation | Endoplasmic Reticulum MembranePeripheral Membrane Protein |
| Alternative Antibody Names | Anti-Lanosterol Synthase antibodyAnti-2 -3-Epoxysqualene--Lanosterol Cyclase antibodyAnti-Oxidosqualene--Lanosterol Cyclase antibodyAnti-Osc antibodyAnti-Hosc antibodyAnti-LSS antibodyAnti-OSC antibody |
Information sourced from Uniprot.org
