Anti-LSP1 antibody (C-Term) (STJ72167)

SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
STJ72167-100
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General Information

Short DescriptionGoat polyclonal antibody anti-LSP1 (C-Term) is suitable for use in ELISA, Western Blot and Immunohistochemistry research applications.
ApplicationsPep-ELISA/WB/IHC
HostGoat
ReactivityHuman/Mouse/Rat/Dog/Cow
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ClonalityPolyclonal
IsotypeIgG
ConjugationUnconjugated
Concentration0.5 mg/mL
PurificationPurified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Dilution RangePeptide ELISA: antibody detection limit dilution 1:16000.
WB: Approx 50kDa band observed in Human Peripheral Blood Mononucleocytes, (PBMs) and Tonsil lysates and in lysates of cell line Daudi, and approx. 50-55kDa in Human Tonsil and Mouse Spleen
Formulation0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA
Storage InstructionStore at-20ยฐC on receipt and minimise freeze-thaw cycles.

Target Information

Gene SymbolLSP1
Gene ID4046
Uniprot IDLSP1_HUMAN
Accession NumberNP_002330.1; NP_001013271.1
Immunogen RegionC-Term
Immunogen SequenceRYKFVATGHGKYEKV
SpecificityThis antibody is expected to recognize both reported isoforms (NP_002330.1; NP_001013271.1). Reported variants represent identical protein: NP_001013273.1, NP_001013271.1, NP_001013272.1

Additional Info

Post Translational Modifications Phosphorylated by casein kinase II, protein kinase C and MAPKAPK2. Phosphorylation by PKC induces translocation from membrane to cytoplasm. Phosphorylation by MAPKAPK2 may regulate neutrophil chemotaxis.
Function May play a role in mediating neutrophil activation and chemotaxis.
Protein Name Lymphocyte-Specific Protein 1
47 Kda Actin-Binding Protein
52 Kda Phosphoprotein
Pp52
Lymphocyte-Specific Antigen Wp34
Cellular Localisation Cell Membrane
Peripheral Membrane Protein
Cytoplasmic Side
Alternative Antibody Names Anti-Lymphocyte-Specific Protein 1 antibody
Anti-47 Kda Actin-Binding Protein antibody
Anti-52 Kda Phosphoprotein antibody
Anti-Pp52 antibody
Anti-Lymphocyte-Specific Antigen Wp34 antibody
Anti-LSP1 antibody
Anti-WP34 antibody

Information sourced from Uniprot.org

Citations

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