Anti-LSM4 antibody (1-139) (STJ28164)

Name: Anti-LSM4 antibody (1-139) (STJ28164)
SKU: STJ28164
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

ClonalityPolyclonal

HostRabbit

ConjugationUnconjugated

IsotypeIgG

STJ28164

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Short Description	Rabbit polyclonal LSM4 (1-139) antibody for use in WB, IP and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents.
Applications	WB/IP/ELISA
Host	Rabbit
Reactivity	Human/Mouse/Rat
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Clonality	Polyclonal
Isotype	IgG
Conjugation	Unconjugated
Concentration	Lot specific
Purification	Affinity purification
Dilution Range	WB:1:500-1:2000 IP:0.5 Mu g-4 Mu g antibody for 200 Mu g-400 Mu g extracts of whole cells ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Formulation	PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3.
Storage Instruction	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol	LSM4
Gene ID	25804
Uniprot ID	LSM4_HUMAN
Immunogen Region	1-139
Immunogen Sequence	MLPLSLLKTAQNHPMLVELK NGETYNGHLVSCDNWMNINL REVICTSRDGDKFWRMPECY IRGSTIKYLRIPDEIIDMVK EEVVAKGRGRGGLQQQKQQK GRGMGGAGRGVFGGRGRGGI PGTGRGQPEKKPGRQAGKQ
Specificity	Recombinant fusion protein containing a sequence corresponding to amino acids 1-139 of human LSM4 (NP_036453.1).

Function	Plays a role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA.
Protein Name	U6 Snrna-Associated Sm-Like Protein Lsm4 Glycine-Rich Protein Grp
Database Links	Reactome: R-HSA-430039 Reactome: R-HSA-72163
Cellular Localisation	Nucleus
Alternative Antibody Names	Anti-U6 Snrna-Associated Sm-Like Protein Lsm4 antibody Anti-Glycine-Rich Protein antibody Anti-Grp antibody Anti-LSM4 antibody

Information sourced from Uniprot.org