Anti-LSM11 antibody (131-360) (STJ29652)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal LSM11 (131-360) antibody for use in WB and ELISA in human and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | LSM11 |
| Gene ID | 134353 |
| Uniprot ID | LSM11_HUMAN |
| Immunogen Region | 131-360 |
| Immunogen Sequence | RRGPGRSRKAPRNVLTRMPL HEGSPLGELHRCIREGVKVN VHIRTFKGLRGVCTGFLVAF DKFWNMALTDVDETYRKPVL GKAYERDSSLTLTRLFDRLK LQDSSKKEADSKSAVEDSTL SRYSQTSTWKLASVWGRADT GRGSHKRSRSVPSSLQASAR EESRSELSGRTTRTDGSSVG GTFSRATTLSRGQSRKKKRK PKVDYQQVFTRHINQIFIRG ENVLLVHLAQ |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 131-360 of human LSM11 (NP_775762.1). |
Additional Info
| Function | Component of the U7 snRNP complex that is involved in the histone 3'-end pre-mRNA processing. Increases U7 snRNA levels but not histone 3'-end pre-mRNA processing activity, when overexpressed. Required for cell cycle progression from G1 to S phases. Binds specifically to the Sm-binding site of U7 snRNA. |
| Protein Name | U7 Snrna-Associated Sm-Like Protein Lsm11 |
| Database Links | Reactome: R-HSA-111367Reactome: R-HSA-73856Reactome: R-HSA-77588 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-U7 Snrna-Associated Sm-Like Protein Lsm11 antibodyAnti-LSM11 antibody |
Information sourced from Uniprot.org