| Short Description : | Rabbit polyclonal anti-U7 snRNA-associated Sm-like protein LSm10 (73-123 aa) for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB |
| Host: | Rabbit |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 1 mg/mL |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range: | WB 1:500-2000 |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | LSM10 |
| Gene ID: | 84967 |
| Uniprot ID: | LSM10_HUMAN |
| Immunogen: | Synthesized peptide derived from the human LSM10 at the amino acid range 73-123 |
| Immunogen Region: | 73-123 aa |
| Specificity: | This antibody detects endogenous levels of LSM10 at Human/Mouse |
| Function | Appears to function in the U7 snRNP complex that is involved in histone 3'-end processing. Increases U7 snRNA levels but not histone 3'-end pre-mRNA processing activity, when overexpressed. Required for cell cycle progression from G1 to S phases. Binds specifically to U7 snRNA. Binds to the downstream cleavage product (DCP) of histone pre-mRNA in a U7 snRNP dependent manner. |
| Protein Name | U7 Snrna-Associated Sm-Like Protein Lsm10 |
| Database Links | Reactome: R-HSA-111367Reactome: R-HSA-73856Reactome: R-HSA-77588 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-U7 Snrna-Associated Sm-Like Protein Lsm10 antibodyAnti-LSM10 antibody |
Information sourced from Uniprot.org
