Anti-LRRC59 antibody (1-244) (STJ112062)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal LRRC59 (1-244) antibody for use in WB, IHC-P and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | LRRC59 |
| Gene ID | 55379 |
| Uniprot ID | LRC59_HUMAN |
| Immunogen Region | 1-244 |
| Immunogen Sequence | MTKAGSKGGNLRDKLDGNEL DLSLSDLNEVPVKELAALPK ATILDLSCNKLTTLPSDFCG LTHLVKLDLSKNKLQQLPAD FGRLVNLQHLDLLNNKLVTL PVSFAQLKNLKWLDLKDNPL DPVLAKVAGDCLDEKQCKQC ANKVLQHMKAVQADQERERQ RRLEVEREAEKKREAKQRAK EAQERELRKREKAEEKERRR KEYDALKAAKREQEKKPKKE ANQAPKSKSGSRPRKPPPR |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-244 of human LRRC59 (NP_060979.2). |
Additional Info
| Tissue Specificity | Widely expressed. |
| Function | Required for nuclear import of FGF1, but not that of FGF2. Might regulate nuclear import of exogenous FGF1 by facilitating interaction with the nuclear import machinery and by transporting cytosolic FGF1 to, and possibly through, the nuclear pores. |
| Protein Name | Leucine-Rich Repeat-Containing Protein 59Ribosome-Binding Protein P34P34 Cleaved Into - Leucine-Rich Repeat-Containing Protein 59 - N-Terminally Processed |
| Database Links | |
| Cellular Localisation | Microsome MembraneSingle-Pass Type Ii Membrane ProteinEndoplasmic Reticulum MembraneNucleus EnvelopeLocalization In The Nuclear Envelope Depends Upon The Nuclear Import MachineryIncluding Kpnb1 |
| Alternative Antibody Names | Anti-Leucine-Rich Repeat-Containing Protein 59 antibodyAnti-Ribosome-Binding Protein P34 antibodyAnti-P34 Cleaved Into - Leucine-Rich Repeat-Containing Protein 59 - N-Terminally Processed antibodyAnti-LRRC59 antibodyAnti-PRO1855 antibody |
Information sourced from Uniprot.org