Anti-LRRC4 antibody (544-653) (STJ112359)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal LRRC4 (544-653) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:1000-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | LRRC4 |
| Gene ID | 64101 |
| Uniprot ID | LRRC4_HUMAN |
| Immunogen Region | 544-653 |
| Immunogen Sequence | LIVFYKLRKRHQQRSTVTAA RTVEIIQVDEDIPAATSAAA TAAPSGVSGEGAVVLPTIHD HINYNTYKPAHGAHWTENSL GNSLHPTVTTISEPYIIQTH TKDKVQETQI |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 544-653 of human LRRC4 (NP_071426.1). |
Additional Info
| Tissue Specificity | Specifically expressed in brain. |
| Post Translational Modifications | N-glycosylated. |
| Function | Synaptic adhesion protein. Regulates the formation of exitatory synapses through the recruitment of pre-and-postsynaptic proteins. Organize the lamina/pathway-specific differentiation of dendrites. Plays an important role for auditory synaptic responses. Involved in the suppression of glioma. |
| Protein Name | Leucine-Rich Repeat-Containing Protein 4Brain Tumor-Associated Protein BagNasopharyngeal Carcinoma-Associated Gene 14 ProteinNetrin-G2 LigandNgl-2 |
| Database Links | |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane ProteinPostsynaptic Cell MembraneLrrc4 And Dlg4 Are Interdependent For Synaptic Localization |
| Alternative Antibody Names | Anti-Leucine-Rich Repeat-Containing Protein 4 antibodyAnti-Brain Tumor-Associated Protein Bag antibodyAnti-Nasopharyngeal Carcinoma-Associated Gene 14 Protein antibodyAnti-Netrin-G2 Ligand antibodyAnti-Ngl-2 antibodyAnti-LRRC4 antibodyAnti-BAG antibodyAnti-NAG14 antibodyAnti-UNQ554 antibodyAnti-PRO1111 antibody |
Information sourced from Uniprot.org