Anti-LRFN1 antibody (Cytoplasmic Domain) (STJ13101320)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthetic peptide from cytoplasmic domain of mouse LRFN1 (Synaptic differentiation enhancing molecule 1) conjugated to an immunogenic carrier protein was used as the antigen.
General Information
| Short Description | Rabbit polyclonal anti-LRFN1 (Cytoplasmic Domain) for use in IHC and WB in Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/WB |
| Host | Rabbit |
| Reactivity | Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | IgG purified |
| Dilution Range | IHC, WB (confirmed by recombinant protein). A dilution of 1:300 to 1:2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications. |
| Formulation | Lyophilised |
| Storage Instruction | Maintain the lyophilised/reconstituted antibodies frozen at-20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
Target Information
| Gene Symbol | Lrfn1 |
| Gene ID | 80749 |
| Uniprot ID | LRFN1_MOUSE |
| Immunogen | A synthetic peptide from cytoplasmic domain of mouse LRFN1 (Synaptic differentiation enhancing molecule 1) conjugated to an immunogenic carrier protein was used as the antigen. |
| Immunogen Region | Cytoplasmic Domain |
| Specificity | Specific for LRFN1. |
Additional Info
| Post Translational Modifications | Glycosylated. |
| Function | Promotes neurite outgrowth in hippocampal neurons. Involved in the regulation and maintenance of excitatory synapses. Induces the clustering of excitatory postsynaptic proteins, including DLG4, DLGAP1, GRIA1 and GRIN1. |
| Protein Name | Leucine-Rich Repeat And Fibronectin Type Iii Domain-Containing Protein 1Synaptic Adhesion-Like Molecule 2Synaptic Differentiation-Enhancing Molecule 1 |
| Database Links | Reactome: R-MMU-8849932 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane ProteinSynapsePostsynaptic Density MembraneDetected In ExcitatoryBut Not InhibitorySynaptic Plasma Membrane |
| Alternative Antibody Names | Anti-Leucine-Rich Repeat And Fibronectin Type Iii Domain-Containing Protein 1 antibodyAnti-Synaptic Adhesion-Like Molecule 2 antibodyAnti-Synaptic Differentiation-Enhancing Molecule 1 antibodyAnti-Lrfn1 antibodyAnti-Salm2 antibodyAnti-Semo1 antibody |
Information sourced from Uniprot.org