Anti-LPP antibody (Internal) (STJ72099)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Goat polyclonal antibody anti-LPP (Internal) is suitable for use in ELISA and Western Blot research applications. |
| Applications | Pep-ELISA/WB |
| Host | Goat |
| Reactivity | Human/Dog/Cow |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range | Peptide ELISA: antibody detection limit dilution 1:16000.WB: Approx 85kDa band observed in Human Placenta lysates and in lysates of cell line HepG2 (calculated MW of 65.7kDa according to NP_005569.1). This molecular weight is routinely observed |
| Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction | Store at-20°C on receipt and minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | LPP |
| Gene ID | 4026 |
| Uniprot ID | LPP_HUMAN |
| Accession Number | NP_005569.1 |
| Immunogen Region | Internal |
| Immunogen Sequence | RNDSDPTYGQQGHP |
Additional Info
| Function | May play a structural role at sites of cell adhesion in maintaining cell shape and motility. In addition to these structural functions, it may also be implicated in signaling events and activation of gene transcription. May be involved in signal transduction from cell adhesion sites to the nucleus allowing successful integration of signals arising from soluble factors and cell-cell adhesion sites. Also suggested to serve as a scaffold protein upon which distinct protein complexes are assembled in the cytoplasm and in the nucleus. |
| Protein Name | Lipoma-Preferred PartnerLim Domain-Containing Preferred Translocation Partner In Lipoma |
| Cellular Localisation | NucleusCytoplasmCell JunctionCell MembraneFound In The NucleusIn The Cytoplasm And At Cell Adhesion SitesShuttles Between The Cytoplasm And The NucleusIt Has Been Found In Sites Of Cell Adhesion Such As Cell-To-Cell Contact And Focal Adhesion Which Are Membrane Attachment Sites Of Cells To The Extracellular MatrixMainly Nuclear When Fused With Hmga2/Hmgic And Kmt2a/Mll1 |
| Alternative Antibody Names | Anti-Lipoma-Preferred Partner antibodyAnti-Lim Domain-Containing Preferred Translocation Partner In Lipoma antibodyAnti-LPP antibody |
Information sourced from Uniprot.org