Anti-LPP antibody (1-100) [S8MR] (STJ11102958)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal LPP (1-100) antibody for use in WB, IHC-P, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | S8MR |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000IHC-P:1:50-1:200IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | LPP |
| Gene ID | 4026 |
| Uniprot ID | LPP_HUMAN |
| Immunogen Region | 1-100 |
| Immunogen Sequence | MSHPSWLPPKSTGEPLGHVP ARMETTHSFGNPSISVSTQQ PPKKFAPVVAPKPKYNPYKQ PGGEGDFLPPPPPPLDDSSA LPSISGNFPPPPPLDEEAFK |
| Specificity | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human LPP (Q93052). |
Additional Info
| Tissue Specificity | Expressed in a wide variety of tissues but no or very low expression in brain and peripheral leukocytes. |
| Function | May play a structural role at sites of cell adhesion in maintaining cell shape and motility. In addition to these structural functions, it may also be implicated in signaling events and activation of gene transcription. May be involved in signal transduction from cell adhesion sites to the nucleus allowing successful integration of signals arising from soluble factors and cell-cell adhesion sites. Also suggested to serve as a scaffold protein upon which distinct protein complexes are assembled in the cytoplasm and in the nucleus. |
| Protein Name | Lipoma-Preferred PartnerLim Domain-Containing Preferred Translocation Partner In Lipoma |
| Database Links | |
| Cellular Localisation | NucleusCytoplasmCell JunctionCell MembraneFound In The NucleusIn The Cytoplasm And At Cell Adhesion SitesShuttles Between The Cytoplasm And The NucleusIt Has Been Found In Sites Of Cell Adhesion Such As Cell-To-Cell Contact And Focal Adhesion Which Are Membrane Attachment Sites Of Cells To The Extracellular MatrixMainly Nuclear When Fused With Hmga2/Hmgic And Kmt2a/Mll1 |
| Alternative Antibody Names | Anti-Lipoma-Preferred Partner antibodyAnti-Lim Domain-Containing Preferred Translocation Partner In Lipoma antibodyAnti-LPP antibody |
Information sourced from Uniprot.org