Anti-LMOD3 antibody (STJA0006840)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human LMOD3
General Information
| Short Description | Rabbit polyclonal anti-Leiomodin-3 for use in WB in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | LMOD3 |
| Gene ID | 56203 |
| Uniprot ID | LMOD3_HUMAN |
| Immunogen | Synthesized peptide derived from human LMOD3 |
| Specificity | This antibody detects endogenous levels of LMOD3 at Human |
Additional Info
| Post Translational Modifications | Ubiquitinated, leading to its degradation. Interaction with KLHL40 negatively regulates ubiquitination and degradation. |
| Function | Essential for the organization of sarcomeric actin thin filaments in skeletal muscle. Increases the rate of actin polymerization. |
| Protein Name | Leiomodin-3Leiomodin - Fetal Form |
| Database Links | |
| Cellular Localisation | CytoplasmMyofibrilSarcomereM LineA BandCytoskeletonHighly Expressed In Nonstriated Areas Of Developing MyotubesWhere It Shows A Granular Cytoplasmic PatternIn SarcomeresHighly Expressed In The M Band Region AndAt Lower LevelsAlong Actin Thin FilamentsNot Detected In Z-DisksMay Be Located NearBut Not AtActin Thin Filament Pointed End |
| Alternative Antibody Names | Anti-Leiomodin-3 antibodyAnti-Leiomodin - Fetal Form antibodyAnti-LMOD3 antibody |
Information sourced from Uniprot.org