| Short Description : | Rabbit polyclonal LMOD1 (29-187) antibody for use in WB, IHC-P and ELISA in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/IHC-P/ELISA |
| Host: | Rabbit |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:2000IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | LMOD1 |
| Gene ID: | 25802 |
| Uniprot ID: | LMOD1_HUMAN |
| Immunogen Region: | 29-187 |
| Immunogen Sequence: | MEELEKELDVVDPDGSVPVG LRQRNQTEKQSTGVYNREAM LNFCEKETKKLMQREMSMDE SKQVETKTDAKNGEERGRDA SKKALGPRRDSDLGKEPKRG GLKKSFSRDRDEAGGKSGEK PKEEKIIRGIDKGRVRAAVD KKEAGKDGRGEERAVATKK |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 29-187 of human LMOD1 (NP_036266.2). |
| Tissue Specificity | Detected in lung vascular smooth muscle (at protein level). Detected in thyroid and extraocular smooth muscle, but not skeletal muscle. Detected in heart, aorta, skeletal muscle, colon, urinary bladder, uterus, stomach, and small intestine. |
| Function | Required for proper contractility of visceral smooth muscle cells. Mediates nucleation of actin filaments. |
| Protein Name | Leiomodin-164 Kda Autoantigen 1d64 Kda Autoantigen 1d364 Kda Autoantigen D1Leiomodin - Muscle FormSmooth Muscle LeiomodinSm-LmodThyroid-Associated Ophthalmopathy Autoantigen |
| Database Links | Reactome: R-HSA-445355 |
| Cellular Localisation | CytoplasmMyofibrilSarcomereCytoskeletonColocalizes With Actin Filaments In Sarcomeres |
| Alternative Antibody Names | Anti-Leiomodin-1 antibodyAnti-64 Kda Autoantigen 1d antibodyAnti-64 Kda Autoantigen 1d3 antibodyAnti-64 Kda Autoantigen D1 antibodyAnti-Leiomodin - Muscle Form antibodyAnti-Smooth Muscle Leiomodin antibodyAnti-Sm-Lmod antibodyAnti-Thyroid-Associated Ophthalmopathy Autoantigen antibodyAnti-LMOD1 antibody |
Information sourced from Uniprot.org
