Anti-LMNB1 antibody [7C11] {AbFluor™ 488} (STJA0006111)

SKU:
STJA0006111

Current Stock:
Host: Mouse
Applications: WB/IHC/IF/IP
Reactivity: Human/Rat/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Mouse monoclonal antibody anti-Lamin-B1 is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and Immunoprecipitation research applications.
Clonality: Monoclonal
Clone ID: 7C11
Conjugation: AbFluor™ 488
Isotype: IgG
Formulation: Liquid in PBS pH7.4, containing 0.02% Sodium Azide and 50% Glycerol.
Purification: The antibody was purified using affinity-chromatography using specific immunogen.
Concentration: 1 mg/mL
Dilution Range: Optimal working dilutions should be determined experimentally by the investigator Suggested starting dilutions are as follows: IHC 1:50-300 IF 1:200
Storage Instruction: Stable for one year at-15°C to-25°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezi
Gene Symbol: LMNB1
Gene ID: 4001
Uniprot ID: LMNB1_HUMAN
Specificity: Lamin B1 Monoclonal Antibody (7C11) AbFluor™ 488 Conjugated specially designed for your Immunofluorescence analysis.
Post Translational Modifications B-type lamins undergo a series of modifications, such as farnesylation and phosphorylation. Increased phosphorylation of the lamins occurs before envelope disintegration and probably plays a role in regulating lamin associations.
Function Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin.
Protein Name Lamin-B1
Database Links Reactome: R-HSA-1221632
Reactome: R-HSA-2559584
Reactome: R-HSA-2980766
Reactome: R-HSA-2995383
Reactome: R-HSA-352238
Reactome: R-HSA-4419969
Reactome: R-HSA-8862803
Reactome: R-HSA-8950505
Reactome: R-HSA-9013405
Reactome: R-HSA-9035034
Cellular Localisation Nucleus Lamina
Alternative Antibody Names Anti-Lamin-B1 antibody
Anti-LMNB1 antibody
Anti-LMN2 antibody
Anti-LMNB antibody

Information sourced from Uniprot.org

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