| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-LIPH (350-450) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
LIPH |
| Gene ID: |
200879 |
| Uniprot ID: |
LIPH_HUMAN |
| Immunogen Region: |
350-450 |
| Immunogen: |
A synthetic peptide corresponding to a sequence within amino acids 350-450 of human LIPH (NP_640341.1). |
| Immunogen Sequence: |
KLRDKAGNTTESKINHEPTT FQKYHQVSLLARFNQDLDKV AAISLMFSTGSLIGPRYKLR ILRMKLRSLAHPERPQLCRY DLVLMENVETVFQPILCPEL Q |
| Tissue Specificity | Present in intestine (at protein level). Expressed in colon, prostate, kidney, pancreas, ovary, testis, intestine, lung and pancreas. Expressed at lower level in brain, spleen and heart. In the skin, it is prominently expressed in hair follicles, including the stem cell-rich bulge region and the inner root sheath. |
| Function | Hydrolyzes specifically phosphatidic acid (PA) to produce 2-acyl lysophosphatidic acid (LPA.a potent bioactive lipid mediator) and fatty acid. Does not hydrolyze other phospholipids, like phosphatidylserine (PS), phosphatidylcholine (PC) and phosphatidylethanolamine (PE) or triacylglycerol (TG). |
| Protein Name | Lipase Member HLiphLpd Lipase-Related ProteinMembrane-Associated Phosphatidic Acid-Selective Phospholipase A1-AlphaMpa-Pla1 AlphaPhospholipase A1 Member B |
| Database Links | Reactome: R-HSA-1483166 |
| Cellular Localisation | SecretedCell MembranePeripheral Membrane Protein |
| Alternative Antibody Names | Anti-Lipase Member H antibodyAnti-Liph antibodyAnti-Lpd Lipase-Related Protein antibodyAnti-Membrane-Associated Phosphatidic Acid-Selective Phospholipase A1-Alpha antibodyAnti-Mpa-Pla1 Alpha antibodyAnti-Phospholipase A1 Member B antibodyAnti-LIPH antibodyAnti-LPDLR antibodyAnti-MPAPLA1 antibodyAnti-PLA1B antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
