| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-LIPG (251-500) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
LIPG |
| Gene ID: |
9388 |
| Uniprot ID: |
LIPG_HUMAN |
| Immunogen Region: |
251-500 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 251-500 of human LIPG (NP_006024.1). |
| Immunogen Sequence: |
GCGLNDVLGSIAYGTITEVV KCEHERAVHLFVDSLVNQDK PSFAFQCTDSNRFKKGICLS CRKNRCNSIGYNAKKMRNKR NSKMYLKTRAGMPFRVYHYQ MKIHVFSYKNMGEIEPTFYV TLYGTNADSQTLPLEIVERI EQNATNTFLVYTEEDLGDLL KIQLTWEGASQSWYNLWKEF RSYLSQPRNPGRELNIRRIR VKSGETQRKLTFCTEDPENT SISPGRELWFRKCRDGWRM |
| Tissue Specificity | High level of expression in the liver, placenta, lung, thyroid, kidney, testis and in the corpus luteum of the ovary. Expressed also in coronary artery endothelial cells, umbilical vein endothelial cells and in hepatocytes and osteosarcoma cell lines. Not detected in heart, brain and muscle. |
| Function | Exerts both phospholipase and triglyceride lipase activities. More active as a phospholipase than a triglyceride lipase. Hydrolyzes triglycerides, both with short-chain fatty acyl groups (tributyrin) and long-chain fatty acyl groups (triolein) with similar levels of activity toward both types of substrates. Hydrolyzes high density lipoproteins (HDL) more efficiently than other lipoproteins. |
| Protein Name | Endothelial LipaseEndothelial Cell-Derived LipaseEdlElPhospholipase A1 |
| Database Links | Reactome: R-HSA-8964058 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Endothelial Lipase antibodyAnti-Endothelial Cell-Derived Lipase antibodyAnti-Edl antibodyAnti-El antibodyAnti-Phospholipase A1 antibodyAnti-LIPG antibodyAnti-UNQ387 antibodyAnti-PRO719 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
