Anti-LIPA antibody [9G7F12/7G6D7] (STJ98212)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG2a
ImmunogenPurified recombinant fragment of LAL expressed in E. Coli.
General Information
| Short Description | Mouse monoclonal anti-Lysosomal acid lipase/cholesteryl ester hydrolase for use in WB and ELISA in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | 9G7F12/7G6D7 |
| Isotype | IgG2a |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | Affinity purification |
| Dilution Range | WB 1:500-1:2000ELISA 1:10000 |
| Formulation | Liquid in PBS containing 0.03% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | LIPA |
| Gene ID | 3988 |
| Uniprot ID | LICH_HUMAN |
| Immunogen | Purified recombinant fragment of LAL expressed in E. Coli. |
| Specificity | LAL Monoclonal Antibody detects endogenous levels of LAL protein. |
Additional Info
| Post Translational Modifications | Glycosylation is not essential for catalytic activity. |
| Function | Catalyzes the deacylation of cholesteryl ester core lipids of endocytosed low density lipoproteins to generate free fatty acids and cholesterol. Hydrolyzes triglycerides (1,2,3-triacylglycerol) and diglycerides (such as 1,2-diacylglycerol and 1,3-diacylglycerol) with preference for the acyl moieties at the sn-1 or sn-3 positions. |
| Protein Name | Lysosomal Acid Lipase/Cholesteryl Ester HydrolaseAcid Cholesteryl Ester HydrolaseLalCholesteryl EsteraseDiacylglycerol LipaseLipase ASterol EsteraseTriacylglycerol Ester HydrolaseTriacylglycerol Lipase |
| Database Links | Reactome: R-HSA-8964038 |
| Cellular Localisation | Lysosome |
| Alternative Antibody Names | Anti-Lysosomal Acid Lipase/Cholesteryl Ester Hydrolase antibodyAnti-Acid Cholesteryl Ester Hydrolase antibodyAnti-Lal antibodyAnti-Cholesteryl Esterase antibodyAnti-Diacylglycerol Lipase antibodyAnti-Lipase A antibodyAnti-Sterol Esterase antibodyAnti-Triacylglycerol Ester Hydrolase antibodyAnti-Triacylglycerol Lipase antibodyAnti-LIPA antibody |
Information sourced from Uniprot.org