| Host: |
Rabbit |
| Applications: |
WB/ELISA |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1 (370-450 aa) is suitable for use in Western Blot and ELISA research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000ELISA 1:5000-20000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
LINGO1 |
| Gene ID: |
84894 |
| Uniprot ID: |
LIGO1_HUMAN |
| Immunogen Region: |
370-450 aa |
| Specificity: |
LIGO1 Polyclonal Antibody detects endogenous levels of protein. |
| Immunogen: |
Synthesized peptide derived from the human protein at the amino acid range 370-450 |
| Post Translational Modifications | N-glycosylated. Contains predominantly high-mannose glycans. |
| Function | Functional component of the Nogo receptor signaling complex (RTN4R/NGFR) in RhoA activation responsible for some inhibition of axonal regeneration by myelin-associated factors. Is also an important negative regulator of oligodentrocyte differentiation and axonal myelination. Acts in conjunction with RTN4 and RTN4R in regulating neuronal precursor cell motility during cortical development. |
| Protein Name | Leucine-Rich Repeat And Immunoglobulin-Like Domain-Containing Nogo Receptor-Interacting Protein 1Leucine-Rich Repeat And Immunoglobulin Domain-Containing Protein 1Leucine-Rich Repeat Neuronal Protein 1Leucine-Rich Repeat Neuronal Protein 6a |
| Database Links | Reactome: R-HSA-193634 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Leucine-Rich Repeat And Immunoglobulin-Like Domain-Containing Nogo Receptor-Interacting Protein 1 antibodyAnti-Leucine-Rich Repeat And Immunoglobulin Domain-Containing Protein 1 antibodyAnti-Leucine-Rich Repeat Neuronal Protein 1 antibodyAnti-Leucine-Rich Repeat Neuronal Protein 6a antibodyAnti-LINGO1 antibodyAnti-LERN1 antibodyAnti-LRRN6A antibodyAnti-UNQ201 antibodyAnti-PRO227 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
