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Anti-LIMS1 antibody [5G7] (STJ98322)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG1
ImmunogenPurified recombinant fragment of human Pinch-1 expressed in E. Coli.
General Information
| Short Description | Mouse monoclonal anti-LIM and senescent cell antigen-like-containing domain protein 1 for use in WB, IF, FC and ELISA in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/FC/ELISA |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | 5G7 |
| Isotype | IgG1 |
| Conjugation | Unconjugated |
| Purification | Affinity purification |
| Dilution Range | WB 1:500-1:2000IF 1:200-1:1000FC 1:200-1:400ELISA 1:10000 |
| Formulation | Liquid in PBS containing 0.03% Sodium Azide, 0.5% BSA, 50% Glycerol. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | LIMS1 |
| Gene ID | 3987 |
| Uniprot ID | LIMS1_HUMAN |
| Immunogen | Purified recombinant fragment of human Pinch-1 expressed in E. Coli. |
| Specificity | Pinch-1 Monoclonal Antibody detects endogenous levels of Pinch-1 protein. |
Additional Info
| Function | Within the IPP (ILK-PINCH-PARVIN) complex, binds to F-actin, promoting F-actin bundling, a process required to generate force for actin cytoskeleton reorganization and subsequent dynamic cell adhesion events such as cell spreading and migration. |
| Protein Name | Lim And Senescent Cell Antigen-Like-Containing Domain Protein 1Particularly Interesting New Cys-His Protein 1Pinch-1Renal Carcinoma Antigen Ny-Ren-48 |
| Database Links | Reactome: R-HSA-446353Reactome: R-HSA-446388 |
| Cellular Localisation | Cell JunctionFocal AdhesionCell MembranePeripheral Membrane ProteinCytoplasmic Side |
| Alternative Antibody Names | Anti-Lim And Senescent Cell Antigen-Like-Containing Domain Protein 1 antibodyAnti-Particularly Interesting New Cys-His Protein 1 antibodyAnti-Pinch-1 antibodyAnti-Renal Carcinoma Antigen Ny-Ren-48 antibodyAnti-LIMS1 antibodyAnti-PINCH antibodyAnti-PINCH1 antibody |
Information sourced from Uniprot.org