Anti-LIG1 antibody (565-790) (STJ24405)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal LIG1 (565-790) antibody for use in WB, IF, ICC and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | LIG1 |
| Gene ID | 3978 |
| Uniprot ID | DNLI1_HUMAN |
| Immunogen Region | 565-790 |
| Immunogen Sequence | CEYKYDGQRAQIHALEGGEV KIFSRNQEDNTGKYPDIISR IPKIKLPSVTSFILDTEAVA WDREKKQIQPFQVLTTRKRK EVDASEIQVQVCLYAFDLIY LNGESLVREPLSRRRQLLRE NFVETEGEFVFATSLDTKDI EQIAEFLEQSVKDSCEGLMV KTLDVDATYEIAKRSHNWLK LKKDYLDGVGDTLDLVVIGA YLGRGKRAGRYGGFLLASYD EDSEEL |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 565-790 of human LIG1 (NP_000225.1). |
Additional Info
| Function | DNA ligase that seals nicks in double-stranded during DNA repair. Also involved in DNA replication and DNA recombination. |
| Protein Name | Dna Ligase 1Dna Ligase IPolydeoxyribonucleotide Synthase Atp 1 |
| Database Links | Reactome: R-HSA-110362Reactome: R-HSA-162594Reactome: R-HSA-174414Reactome: R-HSA-5358565Reactome: R-HSA-5358606Reactome: R-HSA-5651801Reactome: R-HSA-5696397Reactome: R-HSA-6782210Reactome: R-HSA-69183Reactome: R-HSA-9825895 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Dna Ligase 1 antibodyAnti-Dna Ligase I antibodyAnti-Polydeoxyribonucleotide Synthase Atp 1 antibodyAnti-LIG1 antibody |
Information sourced from Uniprot.org