Anti-LIFR antibody (500-700) (STJ114935)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal LIFR (500-700) antibody for use in WB and ELISA in mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | LIFR |
| Gene ID | 3977 |
| Uniprot ID | LIFR_HUMAN |
| Immunogen Region | 500-700 |
| Immunogen Sequence | NPYTLYTFRIRCSTETFWKW SKWSNKKQHLTTEASPSKGP DTWREWSSDGKNLIIYWKPL PINEANGKILSYNVSCSSDE ETQSLSEIPDPQHKAEIRLD KNDYIISVVAKNSVGSSPPS KIASMEIPNDDLKIEQVVGM GKGILLTWHYDPNMTCDYVI KWCNSSRSEPCLMDWRKVPS NSTETVIESDEFRPGIRYNF F |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 500-700 of human LIFR (NP_002301.1). |
Additional Info
| Function | Signal-transducing molecule. May have a common pathway with IL6ST. The soluble form inhibits the biological activity of LIF by blocking its binding to receptors on target cells. |
| Protein Name | Leukemia Inhibitory Factor ReceptorLif ReceptorLif-RCd Antigen Cd118 |
| Database Links | Reactome: R-HSA-6788467Reactome: R-HSA-8939247 |
| Cellular Localisation | Isoform 1: Cell MembraneSingle-Pass Type I Membrane ProteinIsoform 2: Secreted |
| Alternative Antibody Names | Anti-Leukemia Inhibitory Factor Receptor antibodyAnti-Lif Receptor antibodyAnti-Lif-R antibodyAnti-Cd Antigen Cd118 antibodyAnti-LIFR antibody |
Information sourced from Uniprot.org