Anti-LHX3 antibody (250-350) [S7MR] (STJ11103047)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal LHX3 (250-350) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | S7MR |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | LHX3 |
| Gene ID | 8022 |
| Uniprot ID | LHX3_HUMAN |
| Immunogen Region | 250-350 |
| Immunogen Sequence | DSDAEVSFPDEPSLAEMGPA NGLYGSLGEPTQALGRPSGA LGNFSLEHGGLAGPEQYREL RPGSPYGVPPSPAAPQSLPG PQPLLSSLVYPDTSLGLVPS G |
| Specificity | A synthetic peptide corresponding to a sequence within amino acids 250-350 of human LHX3 (Q9UBR4). |
Additional Info
| Function | Transcription factor. Recognizes and binds to the consensus sequence motif 5'-AATTAATTA-3' in the regulatory elements of target genes, such as glycoprotein hormones alpha chain CGA and visual system homeobox CHX10, positively modulating transcription.transcription can be co-activated by LDB2. Synergistically enhances transcription from the prolactin promoter in cooperation with POU1F1/Pit-1. Required for the establishment of the specialized cells of the pituitary gland and the nervous system. Involved in the development of interneurons and motor neurons in cooperation with LDB1 and ISL1. |
| Protein Name | Lim/Homeobox Protein Lhx3Lim Homeobox Protein 3 |
| Database Links | Reactome: R-HSA-9010553 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Lim/Homeobox Protein Lhx3 antibodyAnti-Lim Homeobox Protein 3 antibodyAnti-LHX3 antibody |
Information sourced from Uniprot.org