Anti-LGALS1 antibody (10-90 aa) (STJ93201)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from Galectin-1 at the amino acid range 10-90
General Information
| Short Description | Rabbit polyclonal anti-Galectin-1 (10-90 aa) for use in WB and ELISA in Human, Rat and Deer samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Rat/Deer |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000ELISA 1:40000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20Β°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | LGALS1 |
| Gene ID | 3956 |
| Uniprot ID | LEG1_HUMAN |
| Immunogen | Synthesized peptide derived from Galectin-1 at the amino acid range 10-90 |
| Immunogen Region | 10-90 aa |
| Specificity | Galectin-1 Polyclonal Antibody detects endogenous levels of Galectin-1 protein. |
Additional Info
| Function | Lectin that binds beta-galactoside and a wide array of complex carbohydrates. Plays a role in regulating apoptosis, cell proliferation and cell differentiation. Inhibits CD45 protein phosphatase activity and therefore the dephosphorylation of Lyn kinase. Strong inducer of T-cell apoptosis. Plays a negative role in Th17 cell differentiation via activation of the receptor CD69. |
| Protein Name | Galectin-1Gal-114 Kda Laminin-Binding ProteinHlbp1414 Kda LectinBeta-Galactoside-Binding Lectin L-14-IGalaptinHblHplLactose-Binding Lectin 1Lectin Galactoside-Binding Soluble 1Putative Mapk-Activating Protein Pm12S-Lac Lectin 1 |
| Database Links | Reactome: R-HSA-381426Reactome: R-HSA-8957275 |
| Cellular Localisation | SecretedExtracellular SpaceExtracellular MatrixCytoplasmCan Be SecretedThe Secretion Is Dependent On Protein Unfolding And Facilitated By The Cargo Receptor Tmed10It Results In Protein Translocation From The Cytoplasm Into The Ergic (Endoplasmic Reticulum-Golgi Intermediate Compartment) Followed By Vesicle Entry And Secretion |
| Alternative Antibody Names | Anti-Galectin-1 antibodyAnti-Gal-1 antibodyAnti-14 Kda Laminin-Binding Protein antibodyAnti-Hlbp14 antibodyAnti-14 Kda Lectin antibodyAnti-Beta-Galactoside-Binding Lectin L-14-I antibodyAnti-Galaptin antibodyAnti-Hbl antibodyAnti-Hpl antibodyAnti-Lactose-Binding Lectin 1 antibodyAnti-Lectin Galactoside-Binding Soluble 1 antibodyAnti-Putative Mapk-Activating Protein Pm12 antibodyAnti-S-Lac Lectin 1 antibodyAnti-LGALS1 antibody |
Information sourced from Uniprot.org