• Western blot analysis of lysates from wild type (WT) and Galectin 1/Galectin 1/LGALS1 knockout (KO) 293T cells, using [KO Validated] Galectin 1/LGALS1 Rabbit polyclonal antibody (STJ11100013) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 3min.

Anti-LGALS1 antibody (1-135) (STJ11100013)

SKU:
STJ11100013

Shipping:
Free Shipping
Current Stock:
Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-LGALS1 (1-135) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:1000-1:4000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: LGALS1
Gene ID: 3956
Uniprot ID: LEG1_HUMAN
Immunogen Region: 1-135
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-135 of human Galectin 1/Galectin 1/LGALS1 (NP_002296.1).
Immunogen Sequence: MACGLVASNLNLKPGECLRV RGEVAPDAKSFVLNLGKDSN NLCLHFNPRFNAHGDANTIV CNSKDGGAWGTEQREAVFPF QPGSVAEVCITFDQANLTVK LPDGYEFKFPNRLNLEAINY MAADGDFKIKCVAFD
Tissue Specificity Expressed in placenta, maternal decidua and fetal membranes. Within placenta, expressed in trophoblasts, stromal cells, villous endothelium, syncytiotrophoblast apical membrane and villous stroma. Within fetal membranes, expressed in amnion, chorioamniotic mesenchyma and chorion (at protein level). Expressed in cardiac, smooth, and skeletal muscle, neurons, thymus, kidney and hematopoietic cells.
Function Lectin that binds beta-galactoside and a wide array of complex carbohydrates. Plays a role in regulating apoptosis, cell proliferation and cell differentiation. Inhibits CD45 protein phosphatase activity and therefore the dephosphorylation of Lyn kinase. Strong inducer of T-cell apoptosis.
Protein Name Galectin-1
Gal-1
14 Kda Laminin-Binding Protein
Hlbp14
14 Kda Lectin
Beta-Galactoside-Binding Lectin L-14-I
Galaptin
Hbl
Hpl
Lactose-Binding Lectin 1
Lectin Galactoside-Binding Soluble 1
Putative Mapk-Activating Protein Pm12
S-Lac Lectin 1
Database Links Reactome: R-HSA-381426
Reactome: R-HSA-8957275
Cellular Localisation Secreted
Extracellular Space
Extracellular Matrix
Cytoplasm
Can Be Secreted
The Secretion Is Dependent On Protein Unfolding And Facilitated By The Cargo Receptor Tmed10
It Results In Protein Translocation From The Cytoplasm Into The Ergic (Endoplasmic Reticulum-Golgi Intermediate Compartment) Followed By Vesicle Entry And Secretion
Alternative Antibody Names Anti-Galectin-1 antibody
Anti-Gal-1 antibody
Anti-14 Kda Laminin-Binding Protein antibody
Anti-Hlbp14 antibody
Anti-14 Kda Lectin antibody
Anti-Beta-Galactoside-Binding Lectin L-14-I antibody
Anti-Galaptin antibody
Anti-Hbl antibody
Anti-Hpl antibody
Anti-Lactose-Binding Lectin 1 antibody
Anti-Lectin Galactoside-Binding Soluble 1 antibody
Anti-Putative Mapk-Activating Protein Pm12 antibody
Anti-S-Lac Lectin 1 antibody
Anti-LGALS1 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance