Host: |
Mouse |
Applications: |
ELISA/IHC |
Reactivity: |
Human |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Mouse monoclonal antibody anti-LEC/CCL16/HCC4 is suitable for use in ELISA and Immunohistochemistry research applications. |
Clonality: |
Monoclonal |
Clone ID: |
LEC-57 |
Conjugation: |
Unconjugated |
Isotype: |
IgG1k |
Formulation: |
PBS with 0.02% Sodium Azide. |
Purification: |
Affinity purified from tissue culture. |
Concentration: |
Can be provided as 100 µg/mL, 500 µg/mL or 1mg/mL. |
Dilution Range: |
ELISA (solid phase: 0, 1-100 µg/ml; tracer: 0, 001-100 µg/ml for 30 min at RT). Immunohistology (1-2 µg/ml for 30 min at RT; an appropriate antigen retrieval method for staining of formalin-fixed tissues has not been established to date). |
Storage Instruction: |
Store for up to 1 year at 2-8°C upon receipt. |
Gene Symbol: |
CCL16 |
Gene ID: |
6360 |
Uniprot ID: |
CCL16_HUMAN |
Immunogen: |
A BALB/c mouse was immunized with recombinant human LEC. Fusion partner: NS-1. |
Function | Shows chemotactic activity for lymphocytes and monocytes but not neutrophils. Also shows potent myelosuppressive activity, suppresses proliferation of myeloid progenitor cells. Recombinant SCYA16 shows chemotactic activity for monocytes and THP-1 monocytes, but not for resting lymphocytes and neutrophils. Induces a calcium flux in THP-1 cells that were desensitized by prior expression to RANTES. |
Protein Name | C-C Motif Chemokine 16Chemokine Cc-4Hcc-4Chemokine LecIl-10-Inducible ChemokineLcc-1Liver-Expressed ChemokineLymphocyte And Monocyte ChemoattractantLmcMonotactin-1Mtn-1Ncc-4Small-Inducible Cytokine A16 |
Database Links | Reactome: R-HSA-380108Reactome: R-HSA-418594 |
Cellular Localisation | Secreted |
Alternative Antibody Names | Anti-C-C Motif Chemokine 16 antibodyAnti-Chemokine Cc-4 antibodyAnti-Hcc-4 antibodyAnti-Chemokine Lec antibodyAnti-Il-10-Inducible Chemokine antibodyAnti-Lcc-1 antibodyAnti-Liver-Expressed Chemokine antibodyAnti-Lymphocyte And Monocyte Chemoattractant antibodyAnti-Lmc antibodyAnti-Monotactin-1 antibodyAnti-Mtn-1 antibodyAnti-Ncc-4 antibodyAnti-Small-Inducible Cytokine A16 antibodyAnti-CCL16 antibodyAnti-ILINCK antibodyAnti-NCC4 antibodyAnti-SCYA16 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance