Anti-LEC/CCL16/HCC4 antibody [LEC-14] (STJ16102619)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG1k
ImmunogenA BALB/c mouse was immunized with recombinant human LEC. Fusion partner: NS-1.
General Information
| Short Description | Mouse monoclonal anti-LEC/CCL16/HCC4 for use in ELISA and IHC in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | ELISA/IHC |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | LEC-14 |
| Isotype | IgG1k |
| Conjugation | Unconjugated |
| Concentration | Can be provided as 100 µg/mL, 500 µg/mL or 1mg/mL. |
| Purification | Affinity purified from tissue culture. |
| Dilution Range | ELISA (solid phase: 0, 1-100 µg/ml; tracer: 0, 001-100 µg/ml for 30 min at RT). Immunohistology (1-2 µg/ml for 30 min at RT; an appropriate antigen retrieval method for staining of formalin-fixed tissues has not been established to date). |
| Formulation | PBS with 0.02% Sodium Azide. |
| Storage Instruction | Store for up to 1 year at 2-8°C upon receipt. |
Target Information
| Gene Symbol | CCL16 |
| Gene ID | 6360 |
| Uniprot ID | CCL16_HUMAN |
| Immunogen | A BALB/c mouse was immunized with recombinant human LEC. Fusion partner: NS-1. |
Additional Info
| Function | Shows chemotactic activity for lymphocytes and monocytes but not neutrophils. Also shows potent myelosuppressive activity, suppresses proliferation of myeloid progenitor cells. Recombinant SCYA16 shows chemotactic activity for monocytes and THP-1 monocytes, but not for resting lymphocytes and neutrophils. Induces a calcium flux in THP-1 cells that were desensitized by prior expression to RANTES. |
| Protein Name | C-C Motif Chemokine 16Chemokine Cc-4Hcc-4Chemokine LecIl-10-Inducible ChemokineLcc-1Liver-Expressed ChemokineLymphocyte And Monocyte ChemoattractantLmcMonotactin-1Mtn-1Ncc-4Small-Inducible Cytokine A16 |
| Database Links | Reactome: R-HSA-380108Reactome: R-HSA-418594 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-C-C Motif Chemokine 16 antibodyAnti-Chemokine Cc-4 antibodyAnti-Hcc-4 antibodyAnti-Chemokine Lec antibodyAnti-Il-10-Inducible Chemokine antibodyAnti-Lcc-1 antibodyAnti-Liver-Expressed Chemokine antibodyAnti-Lymphocyte And Monocyte Chemoattractant antibodyAnti-Lmc antibodyAnti-Monotactin-1 antibodyAnti-Mtn-1 antibodyAnti-Ncc-4 antibodyAnti-Small-Inducible Cytokine A16 antibodyAnti-CCL16 antibodyAnti-ILINCK antibodyAnti-NCC4 antibodyAnti-SCYA16 antibody |
Information sourced from Uniprot.org