Anti-LCP1 antibody (1-80 aa) (STJ190106)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human protein at the amino acid range 1-80
General Information
| Short Description | Rabbit polyclonal anti-Plastin-2 (1-80 aa) for use in WB and ELISA in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | LCP1 |
| Gene ID | 3936 |
| Uniprot ID | PLSL_HUMAN |
| Immunogen | Synthesized peptide derived from the human protein at the amino acid range 1-80 |
| Immunogen Region | 1-80 aa |
| Specificity | PLSL Polyclonal Antibody detects endogenous levels of protein. |
Additional Info
| Post Translational Modifications | Phosphorylated on a serine residue in response to costimulation through TCR/CD3 and CD2 or CD28. Serine phosphorylation promotes association with the actin cytoskeleton and targeting to peripheral cell projections. |
| Function | Actin-binding protein. Plays a role in the activation of T-cells in response to costimulation through TCR/CD3 and CD2 or CD28. Modulates the cell surface expression of IL2RA/CD25 and CD69. |
| Protein Name | Plastin-2L-PlastinLc64pLymphocyte Cytosolic Protein 1Lcp-1 |
| Database Links | Reactome: R-HSA-8950505 |
| Cellular Localisation | CytoplasmCytoskeletonCell JunctionCell ProjectionRuffle MembranePeripheral Membrane ProteinCytoplasmic SideRelocalizes To The Immunological Synapse Between Peripheral Blood T-Lymphocytes And Antibody-Presenting Cells In Response To Costimulation Through Tcr/Cd3 And Cd2 Or Cd28Associated With The Actin Cytoskeleton At Membrane RufflesRelocalizes To Actin-Rich Cell Projections Upon Serine Phosphorylation |
| Alternative Antibody Names | Anti-Plastin-2 antibodyAnti-L-Plastin antibodyAnti-Lc64p antibodyAnti-Lymphocyte Cytosolic Protein 1 antibodyAnti-Lcp-1 antibodyAnti-LCP1 antibodyAnti-PLS2 antibody |
Information sourced from Uniprot.org