| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human/Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Late cornified envelope protein 3B (8-58 aa) is suitable for use in Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:1000-2000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | LCE3B |
| Gene ID: | 353143 |
| Uniprot ID: | LCE3B_HUMAN |
| Immunogen Region: | 8-58 aa |
| Specificity: | This antibody detects endogenous levels of human LCE3B |
| Immunogen: | Synthesized peptide derived from the human LCE3B at the amino acid range 8-58 |
| Function | A structural component of the cornified envelope of the stratum corneum involved in innate cutaneous host defense (Probable). Possesses defensin-like antimicrobial activity against a broad spectrum of Gram-positive and Gram-negative bacteria, both aerobic and anaerobic species. Upon inflammation, may regulate skin barrier repair by shaping cutaneous microbiota composition and immune response to bacterial antigens. |
| Protein Name | Late Cornified Envelope Protein 3bLate Envelope Protein 14 |
| Database Links | Reactome: R-HSA-6809371 |
| Alternative Antibody Names | Anti-Late Cornified Envelope Protein 3b antibodyAnti-Late Envelope Protein 14 antibodyAnti-LCE3B antibodyAnti-LEP14 antibody |
Information sourced from Uniprot.org