| Host: |
Goat |
| Applications: |
Pep-ELISA/WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Goat polyclonal antibody anti-LAT2 (Internal) is suitable for use in ELISA and Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: |
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: |
0.5 mg/mL |
| Dilution Range: |
WB-0.01-0.03µg/mlELISA-antibody detection limit dilution 1:128000. |
| Storage Instruction: |
Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: |
LAT2 |
| Gene ID: |
7462 |
| Uniprot ID: |
NTAL_HUMAN |
| Immunogen Region: |
Internal |
| Accession Number: |
NP_054865.2 |
| Specificity: |
Reported variants represent identical protein: NP_115853.2, NP_115852.1, NP_054865.2 |
| Immunogen Sequence: |
RSEKIYQQRSLRED |
| Post Translational Modifications | Phosphorylated on tyrosines following cross-linking of BCR in B-cells, FCGR1 in myeloid cells, or FCER1 in mast cells.which induces the recruitment of GRB2. May be polyubiquitinated. |
| Function | Involved in FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. May also be involved in BCR (B-cell antigen receptor)-mediated signaling in B-cells and FCGR1 (high affinity immunoglobulin gamma Fc receptor I)-mediated signaling in myeloid cells. Couples activation of these receptors and their associated kinases with distal intracellular events through the recruitment of GRB2. |
| Protein Name | Linker For Activation Of T-Cells Family Member 2Linker For Activation Of B-CellsMembrane-Associated Adapter MoleculeNon-T-Cell Activation LinkerWilliams-Beuren Syndrome Chromosomal Region 15 ProteinWilliams-Beuren Syndrome Chromosomal Region 5 Protein |
| Database Links | Reactome: R-HSA-2730905 |
| Cellular Localisation | Cell MembraneSingle-Pass Type Iii Membrane ProteinPresent In Lipid Rafts |
| Alternative Antibody Names | Anti-Linker For Activation Of T-Cells Family Member 2 antibodyAnti-Linker For Activation Of B-Cells antibodyAnti-Membrane-Associated Adapter Molecule antibodyAnti-Non-T-Cell Activation Linker antibodyAnti-Williams-Beuren Syndrome Chromosomal Region 15 Protein antibodyAnti-Williams-Beuren Syndrome Chromosomal Region 5 Protein antibodyAnti-LAT2 antibodyAnti-LAB antibodyAnti-NTAL antibodyAnti-WBS15 antibodyAnti-WBSCR15 antibodyAnti-WBSCR5 antibodyAnti-HSPC046 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
