Anti-LAP3 antibody (260-519) (STJ29181)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal LAP3 (260-519) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | LAP3 |
| Gene ID | 51056 |
| Uniprot ID | AMPL_HUMAN |
| Immunogen Region | 260-519 |
| Immunogen Sequence | VFLEIHYKGSPNANEPPLVF VGKGITFDSGGISIKASANM DLMRADMGGAATICSAIVSA AKLNLPINIIGLAPLCENMP SGKANKPGDVVRAKNGKTIQ VDNTDAEGRLILADALCYAH TFNPKVILNAATLTGAMDVA LGSGATGVFTNSSWLWNKLF EASIETGDRVWRMPLFEHYT RQVVDCQLADVNNIGKYRSA GACTAAAFLKEFVTHPKWAH LDIAGVMTNKDEVPYLRKG |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 260-519 of human LAP3 (NP_056991.2). |
Additional Info
| Function | Cytosolic metallopeptidase that catalyzes the removal of unsubstituted N-terminal hydrophobic amino acids from various peptides. The presence of Zn(2+) ions is essential for the peptidase activity, and the association with other cofactors can modulate the substrate spectificity of the enzyme. For instance, in the presence of Mn(2+), it displays a specific Cys-Gly hydrolyzing activity of Cys-Gly-S-conjugates. Involved in the metabolism of glutathione and in the degradation of glutathione S-conjugates, which may play a role in the control of the cell redox status. |
| Protein Name | Cytosol AminopeptidaseCysteinylglycine-S-Conjugate DipeptidaseLeucine Aminopeptidase 3Lap-3Leucyl AminopeptidasePeptidase SProline AminopeptidaseProlyl Aminopeptidase |
| Database Links | |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Cytosol Aminopeptidase antibodyAnti-Cysteinylglycine-S-Conjugate Dipeptidase antibodyAnti-Leucine Aminopeptidase 3 antibodyAnti-Lap-3 antibodyAnti-Leucyl Aminopeptidase antibodyAnti-Peptidase S antibodyAnti-Proline Aminopeptidase antibodyAnti-Prolyl Aminopeptidase antibodyAnti-LAP3 antibodyAnti-LAPEP antibodyAnti-PEPS antibody |
Information sourced from Uniprot.org