| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-LAP3 (260-519) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
LAP3 |
| Gene ID: |
51056 |
| Uniprot ID: |
AMPL_HUMAN |
| Immunogen Region: |
260-519 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 260-519 of human LAP3 (NP_056991.2). |
| Immunogen Sequence: |
VFLEIHYKGSPNANEPPLVF VGKGITFDSGGISIKASANM DLMRADMGGAATICSAIVSA AKLNLPINIIGLAPLCENMP SGKANKPGDVVRAKNGKTIQ VDNTDAEGRLILADALCYAH TFNPKVILNAATLTGAMDVA LGSGATGVFTNSSWLWNKLF EASIETGDRVWRMPLFEHYT RQVVDCQLADVNNIGKYRSA GACTAAAFLKEFVTHPKWAH LDIAGVMTNKDEVPYLRKG |
| Function | Cytosolic metallopeptidase that catalyzes the removal of unsubstituted N-terminal hydrophobic amino acids from various peptides. The presence of Zn(2+) ions is essential for the peptidase activity, and the association with other cofactors can modulate the substrate spectificity of the enzyme. For instance, in the presence of Mn(2+), it displays a specific Cys-Gly hydrolyzing activity of Cys-Gly-S-conjugates. Involved in the metabolism of glutathione and in the degradation of glutathione S-conjugates, which may play a role in the control of the cell redox status. |
| Protein Name | Cytosol AminopeptidaseCysteinylglycine-S-Conjugate DipeptidaseLeucine Aminopeptidase 3Lap-3Leucyl AminopeptidasePeptidase SProline AminopeptidaseProlyl Aminopeptidase |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Cytosol Aminopeptidase antibodyAnti-Cysteinylglycine-S-Conjugate Dipeptidase antibodyAnti-Leucine Aminopeptidase 3 antibodyAnti-Lap-3 antibodyAnti-Leucyl Aminopeptidase antibodyAnti-Peptidase S antibodyAnti-Proline Aminopeptidase antibodyAnti-Prolyl Aminopeptidase antibodyAnti-LAP3 antibodyAnti-LAPEP antibodyAnti-PEPS antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
