| Short Description : | Rabbit polyclonal anti-Laminin-111 for use in IHC-F and WB in Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | IHC-F/WB |
| Host: | Rabbit |
| Reactivity: | Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Purification: | Affinity purified |
| Dilution Range: | WB 1:1000-1:5000IHC 1:1000-1:5000 |
| Formulation: | Lyophilized from PBS buffer pH 7.2-7.6 with 0.1% trehalose, and sodium azide |
| Storage Instruction: | Spin vial briefly before opening. Reconstitute with 100 µL sterile-filtered, ultrapure water. Centrifuge to remove any insoluble material. Store lyophilized antibody at 2-8°C. After reconstitution divide into aliquots and store at-20°C for long-term |
| Gene Symbol: | Lama1 |
| Gene ID: | 16772 |
| Uniprot ID: | LAMA1_MOUSE |
| Immunogen: | Laminin-111 isolated from mouse EHS cells |
| Immunogen Sequence: | Mouse |
| Specificity: | Reacts with mouse and rat, other species not tested. This antibody recognizes laminin isotypes alpha-1 (440 kDa) , beta-1 (220 kDa) and gamma-1 (220 kDa). It also binds laminin binding protein at 120 kDa which always co-expresses with laminin. |
| Post Translational Modifications | Tyrosine phosphorylated by PKDCC/VLK. |
| Function | Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. |
| Protein Name | Laminin Subunit Alpha-1Laminin A ChainLaminin-1 Subunit AlphaLaminin-3 Subunit AlphaS-Laminin Subunit AlphaS-Lam Alpha |
| Database Links | |
| Cellular Localisation | SecretedExtracellular SpaceExtracellular MatrixBasement MembraneMajor Component |
| Alternative Antibody Names | Anti-Laminin Subunit Alpha-1 antibodyAnti-Laminin A Chain antibodyAnti-Laminin-1 Subunit Alpha antibodyAnti-Laminin-3 Subunit Alpha antibodyAnti-S-Laminin Subunit Alpha antibodyAnti-S-Lam Alpha antibodyAnti-Lama1 antibodyAnti-Lama antibodyAnti-Lama-1 antibody |
Information sourced from Uniprot.org