Anti-LAMB3 antibody (762-1172) (STJ115619)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal LAMB3 (762-1172) antibody for use in WB and ELISA in human and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:100-1:500ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | LAMB3 |
| Gene ID | 3914 |
| Uniprot ID | LAMB3_HUMAN |
| Immunogen Region | 762-1172 |
| Immunogen Sequence | TGSPKLVALRLEMSSLPDLT PTFNKLCGNSRQMACTPISC PGELCPQDNGTACGSRCRGV LPRAGGAFLMAGQVAEQLRG FNAQLQRTRQMIRAAEESAS QIQSSAQRLETQVSASRSQM EEDVRRTRLLIQQVRDFLTD PDTDAATIQEVSEAVLALWL PTDSATVLQKMNEIQAIAAR LPNVDLVLSQTKQDIARARR LQAEAEEARSRAHAVEGQVE DVVGNLRQGTVALQEAQDT |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 762-1004 of human LAMB3 (NP_000219.2). |
Additional Info
| Tissue Specificity | Found in the basement membranes (major component). |
| Function | Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. |
| Protein Name | Laminin Subunit Beta-3Epiligrin Subunit BataKalinin B1 ChainKalinin Subunit BetaLaminin B1k ChainLaminin-5 Subunit BetaNicein Subunit Beta |
| Database Links | Reactome: R-HSA-1474228Reactome: R-HSA-2022090Reactome: R-HSA-2214320Reactome: R-HSA-3000157Reactome: R-HSA-3000171Reactome: R-HSA-446107Reactome: R-HSA-8874081Reactome: R-HSA-9913351 |
| Cellular Localisation | SecretedExtracellular SpaceExtracellular MatrixBasement Membrane |
| Alternative Antibody Names | Anti-Laminin Subunit Beta-3 antibodyAnti-Epiligrin Subunit Bata antibodyAnti-Kalinin B1 Chain antibodyAnti-Kalinin Subunit Beta antibodyAnti-Laminin B1k Chain antibodyAnti-Laminin-5 Subunit Beta antibodyAnti-Nicein Subunit Beta antibodyAnti-LAMB3 antibodyAnti-LAMNB1 antibody |
Information sourced from Uniprot.org